Methylmalonic acidemia is an inherited metabolic disorder,which is caused by deficiency of methylmalonyl-coenzyme A mutase or its cofactor adenosylcobalamin.
Galactosemia is another rare metabolic disorder that occurs when the liver enzyme GALT, needed to break down galactose, is partially or completely absent.
Compromised circadian rhythms are less effective at coordinating organ functioning and can incur health risks like metabolic disorders and vulnerable immune systems.
Also, brain imaging (MRI is preferred) can identify potential structural abnormalities, and blood tests can be done to look for underlying metabolic or genetic disorders.
Heavier individuals tend to have higher blood pressure, higher risks of heart disease, and a greater chance for metabolic disorders like Type 2 diabetes.